The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001861 P54252 ATXN3
ATX3_HUMAN
253 260 ADLRRAIQLSMQGSSRNISQ TP --- Homo sapiens (Human) 364

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Fei,2007 support likely FeatureDetection
experimental MI:0424 protein kinase assay in vivo Fei,2007 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P49841) GSK3B_HUMAN PF00069 (Pkinase)
Protein kinase domain
56 340 [mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P54252 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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