The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001859 P04637 TP53
P53_HUMAN
30 37 KLLPENNVLSPLPSQAMDDL TP --- Homo sapiens (Human) 393

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Turenne,2001 support likely FeatureDetection
experimental MI:0424 protein kinase assay in vivo Turenne,2001 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P49841) GSK3B_HUMAN PF00069 (Pkinase)
Protein kinase domain
56 340 [mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P04637 is implicated in the following 35 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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