The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003830 Q99814 EPAS1
EPAS1_HUMAN
383 389 SGKGAVSEKSNFLFTKLKEE TP --- Homo sapiens (Human) 870

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Pangou,2016 support certain FeatureDetection
experimental MI:0427 Identification by mass spectrometry Pangou,2016 support certain ParticipantIdentification
experimental MI:0424 protein kinase assay in vivo Pangou,2016 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P48730) KC1D_HUMAN PF00069 (Pkinase)
Protein kinase domain
9 267 [mitab][xml]

o  Pathways

KEGG: The sequence Q99814 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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