The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003818 Q8TD43 TRPM4
TRPM4_HUMAN
839 845 LSGGGGSLASGGPGPGHASL TP --- Homo sapiens (Human) 1214

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0051 fluorescence technology Cerda,2015 support certain InteractionDetection
experimental MI:0113 western blot in vitro Cerda,2015 support certain ParticipantIdentification FeatureDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Cerda,2015 support certain FeatureDetection
experimental MI:0032 de novo protein sequencing by mass spectrometry in vivo/in vitro Cerda,2015 support certain ParticipantIdentification FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P49674) KC1E_HUMAN PF00069 (Pkinase)
Protein kinase domain
9 267 [mitab][xml]

o  Pathways

KEGG: The sequence Q8TD43 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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