The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003820 Q16665 HIF1A
HIF1A_HUMAN
244 250 DSKTFLSRHSLDMKFSYCDE TP --- Homo sapiens (Human) 826

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0424 protein kinase assay in vivo Kalousi,2010 support certain InteractionDetection
experimental MI:0586 inhibitor Kalousi,2010 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Kalousi,2010 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P48730) KC1D_HUMAN PF00069 (Pkinase)
Protein kinase domain
9 267 [mitab][xml]

o  Pathways

KEGG: The sequence Q16665 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org