The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003832 Q14457 BECN1
BECN1_HUMAN
409 415 IEDTGGSGGSYSIKTQFNSE TP --- Homo sapiens (Human) 450

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0586 inhibitor Sun,2015 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Sun,2015 support certain FeatureDetection
experimental MI:0113 western blot in vitro Sun,2015 support certain ParticipantIdentification FeatureDetection
experimental MI:0424 protein kinase assay in vivo Sun,2015 support certain InteractionDetection
experimental MI:0427 Identification by mass spectrometry Sun,2015 support certain ParticipantIdentification

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P78368) KC1G2_HUMAN PF00069 (Pkinase)
Protein kinase domain
46 298 [mitab][xml]

o  Pathways

KEGG: The sequence Q14457 is implicated in the following 12 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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