| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003828 | Q00987 MDM2 MDM2_HUMAN |
118 | 124 | QQESSDSGTSVSENRCHLEG | TP | --- | Homo sapiens (Human) | 491 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Inuzuka,2010 | support | certain | FeatureDetection |
| experimental | MI:0586 | inhibitor | Inuzuka,2010 | support | certain | ||
| experimental | MI:0427 | Identification by mass spectrometry | Inuzuka,2010 | support | certain | ParticipantIdentification | |
| experimental | MI:0113 | western blot | in vitro | Inuzuka,2010 | support | certain | ParticipantIdentification FeatureDetection |
| experimental | MI:0424 | protein kinase assay | in vitro | Inuzuka,2010 | support | certain | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P48730) KC1D_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
9 | 267 | [mitab][xml] |
Pathways
- Bladder cancer
- C type lectin receptor signaling pathway
- Cell cycle
- Cellular senescence
- Chronic myeloid leukemia
- Endocrine resistance
- Endocytosis
- Epstein Barr virus infection
- FoxO signaling pathway
- Glioma
- Human cytomegalovirus infection
- Human papillomavirus infection
- Melanoma
- MicroRNAs in cancer
- PI3K Akt signaling pathway
- Pathways in cancer
- Platinum drug resistance
- Prostate cancer
- Proteoglycans in cancer
- Shigellosis
- Thyroid hormone signaling pathway
- Transcriptional misregulation in cancer
- Ubiquitin mediated proteolysis
- Viral carcinogenesis
- p53 signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement