The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003808 P30304 CDC25A
MPIP1_HUMAN
79 85 RMGSSESTDSGFCLDSPGPL TP --- Homo sapiens (Human) 524

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Honaker,2010 support certain FeatureDetection
experimental MI:0586 inhibitor Honaker,2010 support certain
experimental MI:0113 western blot in vitro Honaker,2010 support certain ParticipantIdentification FeatureDetection
experimental MI:0424 protein kinase assay in vitro Honaker,2010 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Honaker,2010 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P48729) KC1A_HUMAN PF00069 (Pkinase)
Protein kinase domain
17 259 [mitab][xml]

o  Pathways

KEGG: The sequence P30304 is implicated in the following 5 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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