The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003824 P13864 Dnmt1
DNMT1_MOUSE
150 156 TLSVETSPSSVATRRTTRQT TP --- Mus musculus (House mouse) 1620

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Sugiyama,2010 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Sugiyama,2010 support certain FeatureDetection
experimental MI:0519 glutathione s tranferase tag in vitro Sugiyama,2010 support certain
experimental MI:0096 pull down in vivo/in vitro Sugiyama,2010 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9DC28) KC1D_MOUSE PF00069 (Pkinase)
Protein kinase domain
9 267 [mitab][xml]
(Q9JMK2) KC1E_MOUSE PF00069 (Pkinase)
Protein kinase domain
9 267 [mitab][xml]

o  Pathways

KEGG: The sequence P13864 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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