The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003229 P04637 TP53
P53_HUMAN
312 319 RALPNNTSSSPQPKKKPLDG TP --- Homo sapiens (Human) 393

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:1297 phosphoamino acid analysis Bischoff,1990 support certain FeatureDetection
experimental Two dimensional phosphopeptide mapping in vitro Bischoff,1990 support certain
experimental MI:0424 protein kinase assay in vitro Bischoff,1990 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Bischoff,1990 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06493) CDK1_HUMAN PF00069 (Pkinase)
Protein kinase domain
4 287 [mitab][xml]

o  Pathways

The sequence P04637 is implicated in the following 35 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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