The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003226 O43464 HTRA2
HTRA2_HUMAN
397 404 VLIHKVILGSPAHRAGLRPG TP --- Homo sapiens (Human) 458

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0586 inhibitor Fitzgerald,2012 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Fitzgerald,2012 support certain InteractionDetection
experimental MI:0113 western blot in vitro Fitzgerald,2012 support certain ParticipantIdentification FeatureDetection
experimental MI:0424 protein kinase assay in vitro Fitzgerald,2012 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Fitzgerald,2012 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q00535) CDK5_HUMAN PF00069 (Pkinase)
Protein kinase domain
4 286 [mitab][xml]
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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