ELM - instance MOD_CDK_SPxxK_3 in sequence O43464 at position 397

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI003226	O43464 HTRA2 HTRA2_HUMAN	397	404	VLIHKVILGSPAHRAGLRPG	TP	---	Homo sapiens (Human)	458

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0586	inhibitor		Fitzgerald,2012	support	certain
experimental	MI:0019	coimmunoprecipitation	in vivo/in vitro	Fitzgerald,2012	support	certain	InteractionDetection
experimental	MI:0113	western blot	in vitro	Fitzgerald,2012	support	certain	ParticipantIdentification FeatureDetection
experimental	MI:0424	protein kinase assay	in vitro	Fitzgerald,2012	support	certain	InteractionDetection
experimental	MI:0005	alanine scanning	in vivo/in vitro/in silico	Fitzgerald,2012	support	certain	FeatureDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(Q00535) CDK5_HUMAN	PF00069 (Pkinase) Protein kinase domain	4	286		[mitab][xml]

Pathways

KEGG: The sequence O43464 is implicated in the following 4 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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