ELM - instance MOD_CDK_SPxxK_3 in sequence O00418 at position 356

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI003210	O00418 EEF2K EF2K_HUMAN	356	363	LRGTEEKCGSPQVRTLSGSR	TP	---	Homo sapiens (Human)	725

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0113	western blot	in vitro	Smith,2008	support	certain	ParticipantIdentification FeatureDetection
experimental	MI:0424	protein kinase assay	in vitro	Smith,2008	support	certain	InteractionDetection
experimental	MI:0424	protein kinase assay	in vivo	Smith,2008	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Smith,2008	support	certain	FeatureDetection
experimental	MI:0586	inhibitor		Smith,2008	support	certain

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(P06493) CDK1_HUMAN	PF00069 (Pkinase) Protein kinase domain	4	287		[mitab][xml]

Pathways

KEGG: The sequence O00418 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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