| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003249 | Q16665 HIF1A HIF1A_HUMAN |
665 | 671 | YRDTQSRTASPNRAGKGVIE | TP | --- | Homo sapiens (Human) | 826 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Warfel,2013 | support | certain | |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Warfel,2013 | support | certain | FeatureDetection |
| experimental | MI:0424 | protein kinase assay | in vitro | Warfel,2013 | support | certain | InteractionDetection |
| experimental | MI:0424 | protein kinase assay | in vivo | Warfel,2013 | support | certain | InteractionDetection |
| experimental | MI:0113 | western blot | in vitro | Warfel,2013 | support | certain | ParticipantIdentification FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P06493) CDK1_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
4 | 287 | [mitab][xml] |
Pathways
- Autophagy animal
- Central carbon metabolism in cancer
- Chemical carcinogenesis reactive oxygen species
- Choline metabolism in cancer
- HIF 1 signaling pathway
- Kaposi sarcoma associated herpesvirus infection
- Mitophagy animal
- PD L1 expression and PD 1 checkpoint pathway in cancer
- Pathways in cancer
- Proteoglycans in cancer
- Renal cell carcinoma
- Th17 cell differentiation
- Thyroid hormone signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement