The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003250 Q07820 MCL1
MCL1_HUMAN
89 95 GAEVPDVTATPARLLFFAPT TP --- Homo sapiens (Human) 350

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0113 western blot in vitro Harley,2010 support certain ParticipantIdentification FeatureDetection
experimental MI:0943 detection by mass spectrometry in vivo/in vitro Harley,2010 support certain InteractionDetection
experimental MI:0086 polyclonal antibody in vitro Harley,2010 support certain ParticipantIdentification FeatureDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Harley,2010 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Harley,2010 support certain InteractionDetection
experimental MI:0586 inhibitor Harley,2010 support certain

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06493) CDK1_HUMAN PF00069 (Pkinase)
Protein kinase domain
4 287 [mitab][xml]

o  Pathways

The sequence Q07820 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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