| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003247 | P25054 APC APC_HUMAN |
1357 | 1363 | AVEFSSGAKSPSKSGAQTPK | TP | --- | Homo sapiens (Human) | 2843 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0424 | protein kinase assay | in vitro | Beamish,2009 | support | certain | InteractionDetection |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Beamish,2009 | support | certain | FeatureDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Beamish,2009 | support | certain | FeatureDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Beamish,2009 | support | certain | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P24941) CDK2_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
4 | 286 | [mitab][xml] |
Pathways
- Alzheimer disease
- Basal cell carcinoma
- Breast cancer
- Colorectal cancer
- Cushing syndrome
- Endometrial cancer
- Gastric cancer
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human papillomavirus infection
- MicroRNAs in cancer
- Pathways in cancer
- Pathways of neurodegeneration multiple diseases
- Regulation of actin cytoskeleton
- Signaling pathways regulating pluripotency of stem cells
- Wnt signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement