The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003259 P06400 RB1
RB_HUMAN
370 376 EEVNVIPPHTPVRTVMNTIQ TP --- Homo sapiens (Human) 928

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0039 edman degradation in vitro Lees,1992 support certain ParticipantIdentification
experimental MI:0943 detection by mass spectrometry in vivo/in vitro Lees,1992 support certain InteractionDetection
experimental Two dimensional phosphopeptide mapping in vitro Lees,1992 support certain
experimental MI:1297 phosphoamino acid analysis Lees,1992 support certain FeatureDetection
experimental MI:0424 protein kinase assay in vitro Lees,1992 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Lees,1992 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06493) CDK1_HUMAN PF00069 (Pkinase)
Protein kinase domain
4 287 [mitab][xml]

o  Pathways

KEGG: The sequence P06400 is implicated in the following 25 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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