Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI003258 | P06400 RB1 RB_HUMAN |
249 | 255 | VIPINGSPRTPRRGQNRSAR | TP | --- | Homo sapiens (Human) | 928 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0039 | edman degradation | in vitro | Lees,1992 | support | certain | ParticipantIdentification |
experimental | MI:0943 | detection by mass spectrometry | in vivo/in vitro | Lees,1992 | support | certain | InteractionDetection |
experimental | Two dimensional phosphopeptide mapping | in vitro | Lees,1992 | support | certain | ||
experimental | MI:1297 | phosphoamino acid analysis | Lees,1992 | support | certain | FeatureDetection | |
experimental | MI:0424 | protein kinase assay | in vitro | Lees,1992 | support | certain | InteractionDetection |
experimental | MI:0424 | protein kinase assay | in vivo | Lees,1992 | support | certain | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P06493) CDK1_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
4 | 287 | [mitab][xml] |
Pathways
KEGG: The sequence P06400 is implicated in the following 25 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Bladder cancer
- Breast cancer
- Cell cycle
- Cellular senescence
- Chemical carcinogenesis receptor activation
- Chronic myeloid leukemia
- Cushing syndrome
- Endocrine resistance
- Epstein Barr virus infection
- Gastric cancer
- Glioma
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human papillomavirus infection
- Kaposi sarcoma associated herpesvirus infection
- Melanoma
- Non small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Prostate cancer
- Small cell lung cancer
- Viral carcinogenesis
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement