ELM - instance MOD_CDK_SPK_2 in sequence O00443 at position 256

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI003240	O00443 PIK3C2A P3C2A_HUMAN	256	261	TDSKVSNLQVSPKSEDISKF	TP	---	Homo sapiens (Human)	1686

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0113	western blot	in vitro	Didichenko,2003	support	certain	ParticipantIdentification FeatureDetection
experimental	MI:0586	inhibitor		Didichenko,2003	support	certain
experimental	MI:0032	de novo protein sequencing by mass spectrometry	in vivo/in vitro	Didichenko,2003	support	certain	ParticipantIdentification FeatureDetection
experimental	MI:0005	alanine scanning	in vivo/in vitro/in silico	Didichenko,2003	support	certain	FeatureDetection
experimental	MI:0412	electrophoretic mobility supershift assay		Didichenko,2003	support	certain	InteractionDetection
experimental	MI:0424	protein kinase assay	in vitro	Didichenko,2003	support	certain	InteractionDetection
experimental	MI:0424	protein kinase assay	in vivo	Didichenko,2003	support	certain	InteractionDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(P06493) CDK1_HUMAN	PF00069 (Pkinase) Protein kinase domain	4	287		[mitab][xml]

Pathways

KEGG: The sequence O00443 is implicated in the following 4 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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