The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002096 Q13541 EIF4EBP1
4EBP1_HUMAN
54 60 GGTRIIYDRKFLMECRNSPV TP --- Homo sapiens (Human) 118

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0403 colocalization in vitro Marcotrigiano,1999 support certain
experimental MI:0018 two hybrid in vivo Ptushkina,1999 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06730) IF4E_HUMAN PF01652 (IF4E)
Eukaryotic initiation factor 4E
38 200 [mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence Q13541 is implicated in the following 9 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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