ELM - instance LIG_WW_1 in sequence P51168 at position 617

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI002168	P51168 SCNN1B SCNNB_HUMAN	617	620	ALPIPGTPPPNYDSLRLQPL	TP	---	Homo sapiens (Human)	640

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0007	anti tag coimmunoprecipitation	in vivo	Zhou,2007	support	certain	InteractionDetection
experimental	MI:0256	rna interference	in vivo	Zhou,2007	support	certain	InteractionDetection
experimental	MI:0997	ubiquitinase assay	in vitro	Zhou,2007	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Zhou,2007	support	certain	FeatureDetection
experimental	MI:0113	western blot	in vitro	Zhou,2007	support	certain	ParticipantIdentification FeatureDetection

Pathways

KEGG: The sequence P51168 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Diseases

Sequence Variation VAR_026522 (Pos 620) has been implicated in Liddle Syndrome; Lidls (O MIM:177200).
Sequence Variation VAR_026521 (Pos 618) has been implicated in Liddle Syndrome; Lidls (O MIM:177200).
Sequence Variation VAR_026520 (Pos 617) has been implicated in Liddle Syndrome; Lidls (O MIM:177200).

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement