The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002457 P05627 Jun
JUN_MOUSE
167 170 YSASLHSEPPVYANLSNFNP TP --- Mus musculus (House mouse) 334

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0997 ubiquitinase assay in vitro Gao,2006 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Gao,2006 support certain InteractionDetection
experimental MI:0997 ubiquitinase assay in vitro Fang,2004 support certain InteractionDetection
experimental MI:0403 colocalization in vitro Fang,2004 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Fang,2004 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Fang,2002 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q8C863) ITCH_MOUSE PF00397 (WW)
WW domain
[mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P05627 is implicated in the following 33 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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