The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004117 B1Q236 syg-1
SYG1_CAEEL
669 674 YNRYEHSYGSFGSGLSTPGG TP --- Caenorhabditis elegans 730

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro Chia,2014 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Chia,2014 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Chia,2014 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Chia,2014 support certain InteractionDetection
experimental MI:0101 sequence based prediction in silico Chia,2014 support certain InteractionDetection
experimental MI:1088 phenotype-based detection assay Chia,2014 support certain InteractionDetection
experimental MI:2286 functional association in vivo/in vitro Chia,2014 support certain InteractionDetection ParticipantIdentification

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9NYB9) ABI2_HUMAN PF07815 (Abi_HHR)
Abl-interactor HHR
93 169 [mitab][xml]
(P62484) ABI2_MOUSE PF07815 (Abi_HHR)
Abl-interactor HHR
93 168 [mitab][xml]
(O44518) CYFIP_CAEEL PF05994 (FragX_IP)
Cytoplasmic Fragile-X interacting family
383 1228 [mitab][xml]
(Q9VF87) CYFIP_DROME PF05994 (FragX_IP)
Cytoplasmic Fragile-X interacting family
385 1244 [mitab][xml]
(Q7L576) CYFP1_HUMAN PF05994 (FragX_IP)
Cytoplasmic Fragile-X interacting family
389 1222 [mitab][xml]
(Q7TMB8) CYFP1_MOUSE PF05994 (FragX_IP)
Cytoplasmic Fragile-X interacting family
389 1222 [mitab][xml]
(Q10929) Q10929_CAEEL PF07815 (Abi_HHR)
Abl-interactor HHR
95 171 [mitab][xml]
(Q9Y0S9) Q9Y0S9_DROME PF07815 (Abi_HHR)
Abl-interactor HHR
105 184 [mitab][xml]
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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