The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002650 Q9UPS6 SETD1B
SET1B_HUMAN
1746 1752 REHVTGCARSEGFYTIDKKD TP 3UVO  
pdb:3UVO 4ES0  
pdb:4ES0
Homo sapiens (Human) 1966

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Dharmarajan,2012 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Dharmarajan,2012 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Dharmarajan,2012 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Dharmarajan,2012 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Zhang,2012 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Zhang,2012 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P61964) WDR5_HUMAN IPR017986 (IPR017986)
WD40-repeat-containing domain
33 331 0.089/0.117 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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