The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002649 O15047 SETD1A
SET1A_HUMAN
1493 1499 REHQTGSARSEGYYPISKKE TP 3UVN  
pdb:3UVN 4EWR  
pdb:4EWR
Homo sapiens (Human) 1707

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Dharmarajan,2012 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Dharmarajan,2012 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Dharmarajan,2012 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Dharmarajan,2012 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Zhang,2012 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Zhang,2012 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P61964) WDR5_HUMAN IPR017986 (IPR017986)
WD40-repeat-containing domain
33 331 0.495/0.587 [mitab][xml]

o  Pathways

KEGG: The sequence O15047 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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