The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004559 P54252 ATXN3
ATX3_HUMAN
281 290 LTSEELRKRREAYFEKQQQK TP --- Homo sapiens (Human) 364

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0047 far western blotting in vitro Boeddrich,2006 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Boeddrich,2006 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Boeddrich,2006 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Boeddrich,2006 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Boeddrich,2006 support certain
experimental MI:0096 pull down in vivo/in vitro Boeddrich,2006 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P55072) TERA_HUMAN IPR003338 (CDC48, N-terminal subdomain)
The CDC48 N-terminal domain is a protein domain found in AAA ATPases including cell division protein 48 (CDC48), VCP-like ATPase (VAT) and N-ethylmaleimide sensitive fusion protein
25 108 [mitab][xml]

o  Pathways

KEGG: The sequence P54252 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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