Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI002155 | P30273 FCER1G FCERG_HUMAN |
62 | 79 | SDGVYTGLSTRNQETYETLK | TP | --- | Homo sapiens (Human) | 86 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0099 | scintillation proximity assay | in vitro | Chen,1996 | support | certain | InteractionDetection |
experimental | MI:0405 | competition binding | in vitro | Chen,1996 | support | certain | InteractionDetection |
experimental | MI:0411 | elisa | in vitro | Chen,1996 | support | certain | InteractionDetection ParticipantIdentification |
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Sen,2008 | support | certain | InteractionDetection |
experimental | MI:0107 | surface plasmon resonance | in vitro | Sen,2008 | support | certain | InteractionDetection FeatureDetection |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000352:
Phosphorylation of Y65 and Y76 in the ITAM motif of High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) induces high-avidity binding to the tandem SH2 domains of Tyrosine-protein kinase SYK (SYK).
Pathways
KEGG: The sequence P30273 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement