The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000024 Q9Y6Q6 TNFRSF11A
TNR11_HUMAN
342 350 EDSFRQMPTEDEYMDRPSQP TP 1LB5  
Homo sapiens (Human) 616

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Ye,2002 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Ye,2002 support certain InteractionDetection FeatureDetection
predicted MI:0101 sequence based prediction in silico Ye,2002 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9Y4K3) TRAF6_HUMAN IPR037309 (TNF receptor-associated factor 6, MATH domain)
TNF receptor-associated factor 6 (TRAF6) regulates a diverse array of processes, including adaptive immunity, innate immunity, bone metabolism and tissue development
351 500 [mitab][xml]

o  Pathways

KEGG: The sequence Q9Y6Q6 is implicated in the following 5 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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