The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000028 P51617 IRAK1
583 591 LQRGPNQPVESDESLGGLSA TP --- Homo sapiens (Human) 712

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Ye,2002 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Ye,2002 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9Y4K3) TRAF6_HUMAN IPR037309 (TNF receptor-associated factor 6, MATH domain)
TNF receptor-associated factor 6 (TRAF6) regulates a diverse array of processes, including adaptive immunity, innate immunity, bone metabolism and tissue development
351 500 79.0/79.0 [mitab][xml]

o  Pathways

KEGG: The sequence P51617 is implicated in the following 19 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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