The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
607 610 GLREPEKASRPVQEQGGAKA TP --- Homo sapiens (Human) 616

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0033 deletion analysis Darnay,1998 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Darnay,1998 support certain InteractionDetection
experimental MI:0113 western blot in vitro Darnay,1998 support certain ParticipantIdentification FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q12933) TRAF2_HUMAN IPR037305 (TNF receptor-associated factor 2, MATH domain)
TNF receptor-associated factor 2 (TRAF2) regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis
334 497 [mitab][xml]

o  Pathways

KEGG: The sequence Q9Y6Q6 is implicated in the following 5 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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