The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001285 P25054 APC
APC_HUMAN
2801 2811 STSARPSQIPTPVNNNTKKR TP --- Homo sapiens (Human) 2843

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Honnappa,2005 support certain
experimental MI:0077 nuclear magnetic resonance in vitro Honnappa,2005 support certain InteractionDetection FeatureDetection
experimental MI:0017 classical fluorescence spectroscopy in vitro Honnappa,2005 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Honnappa,2005 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Honnappa,2005 support certain FeatureDetection

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P25054 is implicated in the following 10 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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