The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004780 Q9QUN3 Blnk
BLNK_MOUSE
204 212 PAEKAPMVNRSTKPNSSSKH TP --- Mus musculus (House mouse) 457

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0033 deletion analysis Berry,2002 support certain FeatureDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Berry,2002 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Berry,2002 support certain
experimental MI:0421 identification by antibody Berry,2002 support certain ParticipantIdentification
experimental MI:0113 western blot in vitro Berry,2002 support certain ParticipantIdentification FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Berry,2002 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Berry,2002 support certain

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O75791) GRAP2_HUMAN IPR001452 (SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues
271 330 0.53/0.69 [mitab][xml]
(P62993) GRB2_HUMAN IPR001452 (SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues
156 215 10.0/16.0 [mitab][xml]
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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