The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004801 Q9H706 GAREM1
GARE1_HUMAN
532 541 CRLLNAPPVPPRSAKPLSTS TP --- Homo sapiens (Human) 876

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0018 two hybrid in vivo Luck,2020 support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Tashiro,2009 support likely
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Tashiro,2009 support likely FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Tashiro,2009 support likely FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Tashiro,2009 support likely InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Tashiro,2009 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O75791) GRAP2_HUMAN IPR001452 (SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues
271 330 [mitab][xml]
(P62993) GRB2_HUMAN IPR001452 (SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues
156 215 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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