The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004407 Q8WUM4 PDCD6IP
PDC6I_HUMAN
740 745 GGHAPTPPTPAPRTMPPTKP TP --- Homo sapiens (Human) 868

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0416 fluorescence microscopy Rouka,2015 support certain InteractionDetection
experimental MI:0007 anti tag coimmunoprecipitation in vivo Rouka,2015 support certain InteractionDetection
experimental MI:0113 western blot in vitro Rouka,2015 support certain ParticipantIdentification FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Rouka,2015 support certain InteractionDetection FeatureDetection
experimental MI:0047 far western blotting in vitro Rouka,2015 support certain InteractionDetection
experimental MI:0091 chromatography technology in vitro Rouka,2015 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Rouka,2015 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Rouka,2015 support certain InteractionDetection
experimental MI:0818 molecular weight estimation by coomasie staining Rouka,2015 support certain ParticipantIdentification
experimental MI:0808 comigration in sds page in vitro Rouka,2015 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Rouka,2015 support certain
experimental MI:0081 peptide array Rouka,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9Y5K6) CD2AP_HUMAN PF14604 (SH3_9)
Variant SH3 domain
6 55 4.2/6.6 [mitab][xml]
(Q9Y5K6) CD2AP_HUMAN PF14604 (SH3_9)
Variant SH3 domain
115 163 [mitab][xml]

o  Pathways

KEGG: The sequence Q8WUM4 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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