The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004424 Q8TB24 RIN3
RIN3_HUMAN
383 388 LPAKKNLPTAPPRRRVSERV TP 4WCI  
Homo sapiens (Human) 985

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0416 fluorescence microscopy Rouka,2015 support certain InteractionDetection
experimental MI:0007 anti tag coimmunoprecipitation in vivo Rouka,2015 support certain InteractionDetection
experimental MI:0113 western blot in vitro Rouka,2015 support certain ParticipantIdentification FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Rouka,2015 support certain InteractionDetection FeatureDetection
experimental MI:0047 far western blotting in vitro Rouka,2015 support certain InteractionDetection
experimental MI:0091 chromatography technology in vitro Rouka,2015 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Rouka,2015 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Rouka,2015 support certain InteractionDetection
experimental MI:0818 molecular weight estimation by coomasie staining Rouka,2015 support certain ParticipantIdentification
experimental MI:0808 comigration in sds page in vitro Rouka,2015 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Rouka,2015 support certain
experimental MI:0081 peptide array Rouka,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9Y5K6) CD2AP_HUMAN PF14604 (SH3_9)
Variant SH3 domain
6 55 8.9/8.9 [mitab][xml]
(Q9Y5K6) CD2AP_HUMAN PF14604 (SH3_9)
Variant SH3 domain
115 163 10.0/10.0 [mitab][xml]
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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