The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004401 Q6ISU1 PTCRA
PTCRA_HUMAN
211 216 GREATSSPRPQPRDRRWGDT TP --- Homo sapiens (Human) 281

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0113 western blot in vitro Navarro,2007 support certain ParticipantIdentification FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Navarro,2007 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Navarro,2007 support certain
experimental MI:0007 anti tag coimmunoprecipitation in vivo Navarro,2007 support certain InteractionDetection
experimental MI:0033 deletion analysis Navarro,2007 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Navarro,2007 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9Y5K6) CD2AP_HUMAN PF14604 (SH3_9)
Variant SH3 domain
6 55 [mitab][xml]
(Q96B97) SH3K1_HUMAN PF14604 (SH3_9)
Variant SH3 domain
6 54 [mitab][xml]

o  Pathways

KEGG: The sequence Q6ISU1 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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