The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004385 P26651 ZFP36
TTP_HUMAN
309 314 GVFAPPQPVAAPRRLPIFNR TP --- Homo sapiens (Human) 326

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0506 over expressed level in vivo Kedar,2010 support certain
experimental MI:0018 two hybrid in vivo Kedar,2010 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Kedar,2010 support certain FeatureDetection
experimental MI:0113 western blot in vitro Kedar,2010 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Kedar,2010 support certain InteractionDetection
experimental MI:0663 confocal microscopy in vivo/in vitro Kedar,2010 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q96B97) SH3K1_HUMAN PF14604 (SH3_9)
Variant SH3 domain
6 54 [mitab][xml]
(Q96B97) SH3K1_HUMAN PF14604 (SH3_9)
Variant SH3 domain
105 153 [mitab][xml]
(Q96B97) SH3K1_HUMAN PF14604 (SH3_9)
Variant SH3 domain
274 324 [mitab][xml]

o  Pathways

KEGG: The sequence P26651 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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