The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003878 Q9QZS7-2 Nphs1
1216 1222 KYEDPRGIYDQVAADMDAGE TP --- Mus musculus (House mouse) 1242

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Blasutig,2008 support certain InteractionDetection
experimental MI:0113 western blot in vitro Blasutig,2008 support certain ParticipantIdentification FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Blasutig,2008 support certain FeatureDetection
experimental MI:0051 fluorescence technology Blasutig,2008 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P16333) NCK1_HUMAN PF00017 (SH2)
SH2 domain
282 356 0.73/1.37 [mitab][xml]
(O43639) NCK2_HUMAN PF00017 (SH2)
SH2 domain
285 359 0.76/0.88 [mitab][xml]
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement