Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI003873 | P09619 PDGFRB PGFRB_HUMAN |
1007 | 1013 | PLDTSSVLYTAVQPNEGDND | TP | --- | Homo sapiens (Human) | 1106 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0107 | surface plasmon resonance | in vitro | Frese,2006 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P16333) NCK1_HUMAN | PF00017
(SH2)
SH2 domain |
282 | 356 | 26.0/28.0 | [mitab][xml] |
(O43639) NCK2_HUMAN | PF00017
(SH2)
SH2 domain |
285 | 359 | 170.0/290.0 | [mitab][xml] |
Pathways
KEGG: The sequence P09619 is implicated in the following 19 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Calcium signaling pathway
- Central carbon metabolism in cancer
- Choline metabolism in cancer
- EGFR tyrosine kinase inhibitor resistance
- Focal adhesion
- Gap junction
- Glioma
- Human papillomavirus infection
- JAK STAT signaling pathway
- MAPK signaling pathway
- Melanoma
- MicroRNAs in cancer
- PI3K Akt signaling pathway
- Pathways in cancer
- Phospholipase D signaling pathway
- Prostate cancer
- Rap1 signaling pathway
- Ras signaling pathway
- Regulation of actin cytoskeleton
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement