The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003699 Q02858 Tek
TIE2_MOUSE
1100 1103 RMLEERKTYVNTTLYEKFTY TP --- Mus musculus (House mouse) 1122

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0107 surface plasmon resonance in vitro Jones,1999 support certain InteractionDetection FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Jones,1999 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Jones,1999 support certain FeatureDetection
experimental MI:0081 peptide array Jones,1999 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Jones,1999 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q60631) GRB2_MOUSE PF00017 (SH2)
SH2 domain
60 135 0.011/0.011 [mitab][xml]
(Q03160) GRB7_MOUSE PF00017 (SH2)
SH2 domain
434 515 0.091/0.091 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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