ELM - instance LIG_SH2_GRB2like in sequence Q02858 at position 1100

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI003699	Q02858 Tek TIE2_MOUSE	1100	1103	RMLEERKTYVNTTLYEKFTY	TP	---	Mus musculus (House mouse)	1122

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0107	surface plasmon resonance	in vitro	Jones,1999	support	certain	InteractionDetection FeatureDetection
experimental	MI:0019	coimmunoprecipitation	in vivo/in vitro	Jones,1999	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Jones,1999	support	certain	FeatureDetection
experimental	MI:0081	peptide array		Jones,1999	support	certain	InteractionDetection
experimental	MI:0018	two hybrid	in vivo	Jones,1999	support	certain	InteractionDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(Q60631) GRB2_MOUSE	PF00017 (SH2) SH2 domain	60	135	0.011/0.011	[mitab][xml]
(Q03160) GRB7_MOUSE	PF00017 (SH2) SH2 domain	434	515	0.091/0.091	[mitab][xml]

Pathways

KEGG: The sequence Q02858 is implicated in the following 6 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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