The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003691 P30203 CD6
CD6_HUMAN
629 632 SSTSSGEWYQNFQPPPQPPS TP --- Homo sapiens (Human) 668

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro Breuning,2017 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Breuning,2017 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Breuning,2017 support certain InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Breuning,2017 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O75791) GRAP2_HUMAN PF00017 (SH2)
SH2 domain
58 132 1.0/3.0 [mitab][xml]
(P62993) GRB2_HUMAN PF00017 (SH2)
SH2 domain
60 135 2.0/4.0 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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