| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI000813 | P04626 ERBB2 ERBB2_HUMAN |
1139 | 1142 | LTCSPQPEYVNQPDVRPQPP | TP |
1MW4 
|
Homo sapiens (Human) | 1255 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Ivancic,2005 | support | certain | InteractionDetection |
| experimental | MI:0077 | nuclear magnetic resonance | in vitro | Ivancic,2003 | support | certain | InteractionDetection FeatureDetection |
| not annotated | not specified | Dankort,2001 | not specified | not specified |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (Q14451) GRB7_HUMAN | PF00017
(SH2)
SH2 domain |
431 | 512 | 2.13/2.43 | [mitab][xml] |
Pathways
- Adherens junction
- Bladder cancer
- Breast cancer
- Calcium signaling pathway
- Central carbon metabolism in cancer
- EGFR tyrosine kinase inhibitor resistance
- Endocrine resistance
- Endometrial cancer
- ErbB signaling pathway
- Focal adhesion
- Gastric cancer
- HIF 1 signaling pathway
- MAPK signaling pathway
- MicroRNAs in cancer
- Non small cell lung cancer
- PI3K Akt signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Platinum drug resistance
- Prostate cancer
- Proteoglycans in cancer
- Tight junction
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement