The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003693 P00533 EGFR
1092 1095 DTFLPVPEYINQSVPKRPAG TP --- Homo sapiens (Human) 1210

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Batzer,1994 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Batzer,1994 support certain InteractionDetection
experimental MI:0968 biosensor Batzer,1994 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P62993) GRB2_HUMAN PF00017 (SH2)
SH2 domain
60 135 0.03/0.03 [mitab][xml]

o  Pathways

KEGG: The sequence P00533 is implicated in the following 48 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement