The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003693 P00533 EGFR
EGFR_HUMAN
1092 1095 DTFLPVPEYINQSVPKRPAG TP --- Homo sapiens (Human) 1210

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Batzer,1994 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Batzer,1994 support certain InteractionDetection
experimental MI:0968 biosensor Batzer,1994 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P62993) GRB2_HUMAN PF00017 (SH2)
SH2 domain
60 135 0.03/0.03 [mitab][xml]

o  Pathways

KEGG: The sequence P00533 is implicated in the following 32 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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