The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003716 P22681 CBL
CBL_HUMAN
774 778 SENEDDGYDVPKPPVPAVLA TP --- Homo sapiens (Human) 906

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0405 competition binding in vitro Reedquist,1996 support certain InteractionDetection
experimental MI:0113 western blot in vitro Reedquist,1996 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Reedquist,1996 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P46108) CRK_HUMAN PF00017 (SH2)
SH2 domain
13 104 [mitab][xml]

o  Pathways

KEGG: The sequence P22681 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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