Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI003742 | P19174 PLCG1 PLCG1_HUMAN |
1253 | 1257 | EGSFESRYQQPFEDFRISQE | FP | --- | Homo sapiens (Human) | 1290 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Shigeno-Nakazawa,2016 | support | unlikely | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P46108) CRK_HUMAN | PF00017
(SH2)
SH2 domain |
13 | 104 | 6.45/6.45 | [mitab][xml] |
Pathways
KEGG: The sequence P19174 is implicated in the following 45 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AGE RAGE signaling pathway in diabetic complications
- Axon guidance
- Calcium signaling pathway
- Chemokine signaling pathway
- Choline metabolism in cancer
- Coronavirus disease COVID 19
- EGFR tyrosine kinase inhibitor resistance
- Epithelial cell signaling in Helicobacter pylori infection
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R mediated phagocytosis
- Glioma
- Growth hormone synthesis, secretion and action
- HIF 1 signaling pathway
- Hepatocellular carcinoma
- Human immunodeficiency virus 1 infection
- Inflammatory mediator regulation of TRP channels
- Inositol phosphate metabolism
- Kaposi sarcoma associated herpesvirus infection
- Leukocyte transendothelial migration
- Lipid and atherosclerosis
- Metabolic pathways
- MicroRNAs in cancer
- NF kappa B signaling pathway
- Natural killer cell mediated cytotoxicity
- Neurotrophin signaling pathway
- Neutrophil extracellular trap formation
- Non small cell lung cancer
- PD L1 expression and PD 1 checkpoint pathway in cancer
- Parkinson disease
- Pathways in cancer
- Pathways of neurodegeneration multiple diseases
- Phosphatidylinositol signaling system
- Phospholipase D signaling pathway
- Proteoglycans in cancer
- Rap1 signaling pathway
- Ras signaling pathway
- Shigellosis
- T cell receptor signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Thyroid hormone signaling pathway
- VEGF signaling pathway
- Vibrio cholerae infection
- Yersinia infection
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement