| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003714 | P16234 PDGFRA PGFRA_HUMAN |
762 | 766 | SDIQRSLYDRPASYKKKSML | FP | --- | Homo sapiens (Human) | 1089 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Shigeno-Nakazawa,2016 | support | unlikely | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Matsumoto,2000 | support | unlikely | FeatureDetection |
| experimental | MI:0113 | western blot | in vitro | Matsumoto,2000 | support | unlikely | ParticipantIdentification FeatureDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Matsumoto,2000 | support | unlikely | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P46108) CRK_HUMAN | PF00017
(SH2)
SH2 domain |
13 | 104 | 0.98/0.98 | [mitab][xml] |
Pathways
- Calcium signaling pathway
- Central carbon metabolism in cancer
- Choline metabolism in cancer
- EGFR tyrosine kinase inhibitor resistance
- Endocytosis
- Focal adhesion
- Gap junction
- Glioma
- Human cytomegalovirus infection
- JAK STAT signaling pathway
- MAPK signaling pathway
- Melanoma
- MicroRNAs in cancer
- PI3K Akt signaling pathway
- Pathways in cancer
- Phospholipase D signaling pathway
- Prostate cancer
- Rap1 signaling pathway
- Ras signaling pathway
- Regulation of actin cytoskeleton
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement