The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003714 P16234 PDGFRA
762 766 SDIQRSLYDRPASYKKKSML FP --- Homo sapiens (Human) 1089

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Shigeno-Nakazawa,2016 support unlikely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Matsumoto,2000 support unlikely FeatureDetection
experimental MI:0113 western blot in vitro Matsumoto,2000 support unlikely ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Matsumoto,2000 support unlikely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P46108) CRK_HUMAN PF00017 (SH2)
SH2 domain
13 104 0.98/0.98 [mitab][xml]

o  Pathways

KEGG: The sequence P16234 is implicated in the following 20 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement