| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003725 | P08069 IGF1R IGF1R_HUMAN |
973 | 977 | RLGNGVLYASVNPEYFSAAD | FP | --- | Homo sapiens (Human) | 1367 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0096 | pull down | in vivo/in vitro | Koval,1998 | support | unlikely | InteractionDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Koval,1998 | support | unlikely | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Koval,1998 | support | unlikely | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (Q64010) CRK_MOUSE | PF00017
(SH2)
SH2 domain |
13 | 104 | [mitab][xml] |
Pathways
- AMPK signaling pathway
- Adherens junction
- Autophagy animal
- Breast cancer
- EGFR tyrosine kinase inhibitor resistance
- Endocrine resistance
- Endocytosis
- Focal adhesion
- FoxO signaling pathway
- Glioma
- HIF 1 signaling pathway
- Hepatocellular carcinoma
- Long term depression
- Longevity regulating pathway
- Longevity regulating pathway multiple species
- MAPK signaling pathway
- Melanoma
- Oocyte meiosis
- Ovarian steroidogenesis
- PI3K Akt signaling pathway
- Pathways in cancer
- Progesterone mediated oocyte maturation
- Prostate cancer
- Proteoglycans in cancer
- Rap1 signaling pathway
- Ras signaling pathway
- Signaling pathways regulating pluripotency of stem cells
- Transcriptional misregulation in cancer
- mTOR signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement