The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003725 P08069 IGF1R
IGF1R_HUMAN
973 977 RLGNGVLYASVNPEYFSAAD FP --- Homo sapiens (Human) 1367

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro Koval,1998 support unlikely InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Koval,1998 support unlikely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Koval,1998 support unlikely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q64010) CRK_MOUSE PF00017 (SH2)
SH2 domain
13 104 [mitab][xml]

o  Pathways

KEGG: The sequence P08069 is implicated in the following 29 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org