The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003141 Q13547 HDAC1
HDAC1_HUMAN
411 428 SDKRIACEEEFSDSEEEGEG TP --- Homo sapiens (Human) 482

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Singh,2005 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Vortmeyer,1999 support certain InteractionDetection
experimental MI:0059 gst pull down in vivo/in vitro Vortmeyer,1999 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Vortmeyer,1999 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Ferreira,1998 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Ferreira,1998 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Ferreira,1998 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Luo,1998 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Magnaghi-Jaulin,1998 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Magnaghi-Jaulin,1998 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Magnaghi-Jaulin,1998 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Brehm,1998 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Brehm,1998 contradict likely InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Brehm,1998 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
646 765 [mitab][xml]

o  Pathways

The sequence Q13547 is implicated in the following 12 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org