The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003118 P24385 CCND1
CCND1_HUMAN
2 19 MEHQLLCCEVETIRRAYPDA TP 2W96  
Homo sapiens (Human) 295

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0405 competition binding in vitro Dowdy,1993 support likely InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Dowdy,1993 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Dowdy,1993 support likely FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Day,2009 support likely InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
646 765 [mitab][xml]

o  Pathways

The sequence P24385 is implicated in the following 32 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org