The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003143 O14777 NDC80
NDC80_HUMAN
229 245 YTIKCYESFMSGADSFDEMN TP 2VE7  
Homo sapiens (Human) 642

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Zheng,2000 support likely
experimental MI:0114 x-ray crystallography in vitro Ciferri,2008 contradict likely InteractionDetection FeatureDetection
experimental MI:0018 two hybrid in vivo Zheng,2000 contradict likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Zheng,2000 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
646 765 [mitab][xml]

o  Pathways

Reactome: The sequence O14777 is implicated in the following 0 Pathways:
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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