The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003490 Q9Y253 POLH
Homo sapiens (Human) 713

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0017 classical fluorescence spectroscopy in vitro Gabel,2013 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Pozhidaeva,2012 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Pozhidaeva,2012 support certain InteractionDetection FeatureDetection
experimental MI:0010 beta galactosidase complementation Ohashi,2009 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Ohashi,2009 support certain FeatureDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Ohashi,2009 support certain
experimental MI:0018 two hybrid in vivo Ohashi,2009 support certain InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Ohashi,2009 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9UBZ9) REV1_HUMAN PF16727 (REV1_C)
DNA repair protein REV1 C-terminal domain
1167 1248 4.4/4.4 [mitab][xml]

o  Pathways

KEGG: The sequence Q9Y253 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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